SteMaxOne™ Program
The SteMaxOne™ Program comprises products and services to support scientists to develop their own proprietary chemically defined media for stem cell culture.
The program consists of three distinct steps:
- Evaluation of currently used material & methods
Stem cell culture media need to be optimised in terms of galenic formulation, preparation and use in order to minimise physico-chemical instabilities of the micro-environment. We directly show to cell biologists how to improve their nutrient mixtures to achieve the target application starting from classic culture media. Such media are often characterised by a sub-optimal nutrient balance and contain animal-derived components or complex additives. Typical applications of improved or newly designed media formulations include routine maintenance and mass cell cultivation with fortified nutrient mixtures.
- Know-how transfer, tech support and express delivery of research-grade material
The above scientific discussion is followed by our know-how transfer & tech support with respect to the development of culture media formulations. Identifying essential nutrients with their suitable concentrations and optimising the bioavailability of water-unsoluble ingredients is the key to define the most suitable stem cell micro-environment. Newly developed and/or improved media are prepared according to our fast-track manufacturing know-how that guarantees delivery of the most preferred media formulations within 20 days. We manufacture media as liquid concentrates to be reconstituted with tissue culture water and filter-sterilised prior to use. The lot size ranges from just 3 liters to 2400 liters research-grade material exclusively containing certified ingredients.
- Manufacturing of GMP-grade material
The above research-grade media can be manufactured as liquid concentrates under cGMP by our pharma partners.
The above steps 1, 2 and 3 can be combined according to the most preferred strategies and goals, e.g. steps 1 through 3, steps 1 & 2 only, step 2 only (express delivery of research-grade material), step 3 only (manufacturing of GMP-grade material), etc.
Stem cell culture media need to be optimised in terms of galenic formulation, preparation and use in order to minimise physico-chemical instabilities of the micro-environment. We directly show to cell biologists how to improve their nutrient mixtures to achieve the target application starting from classic culture media. Such media are often characterised by a sub-optimal nutrient balance and contain animal-derived components or complex additives. Typical applications of improved or newly designed media formulations include routine maintenance and mass cell cultivation with fortified nutrient mixtures.
The above scientific discussion is followed by our know-how transfer & tech support with respect to the development of culture media formulations. Identifying essential nutrients with their suitable concentrations and optimising the bioavailability of water-unsoluble ingredients is the key to define the most suitable stem cell micro-environment. Newly developed and/or improved media are prepared according to our fast-track manufacturing know-how that guarantees delivery of the most preferred media formulations within 20 days. We manufacture media as liquid concentrates to be reconstituted with tissue culture water and filter-sterilised prior to use. The lot size ranges from just 3 liters to 2400 liters research-grade material exclusively containing certified ingredients.
The above research-grade media can be manufactured as liquid concentrates under cGMP by our pharma partners.
The above steps 1, 2 and 3 can be combined according to the most preferred strategies and goals, e.g. steps 1 through 3, steps 1 & 2 only, step 2 only (express delivery of research-grade material), step 3 only (manufacturing of GMP-grade material), etc.
SteMaxOne™ is a trademark of Dr. F. Messi Cell Culture Technologies.